Delta508 is considered a Class II Mutation.
621+1G->T is considered a Class I Mutation.
Both mutations are associated with the "Classic" or "Typical" CF, also considered "severe" in the way of how much the gene does not work properly.
This information is found at: http://aje.oxfordjournals.org/cgi/content/full/159/6/537/KWH083TB1
The best thing the CF Foundation is doing that you've probably never heard of... - If you are in the CF community and haven't heard of it yet, you will soon enough. It's making it's ripples and those ripples are mighty. It's called the ...
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